From routine to unexpected bleeds, surgeons around the world trust FLOSEAL hemostatic matrix to stop various bleeding grades. FLOSEAL’s superior performance and range of applicator tips provide precise delivery to promote healing at the site of surgery.
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Floseal Fast Prep Boxes

The Next Generation of FLOSEAL

Faster Preparation - 15% faster preparation time compared to SURGIFLO1

Easier Reconstitution - 20% less components* and 20% less preparation steps compared to FLOSEAL Full Sterile Prep2,3

Most Preferred Configuration - Ranked #1 by Operating Room Registered Nurses1

*Based on preparation components only.

Floseal 20 Year

Choose Better Outcomes. Choose FLOSEAL.

Inadequate surgical hemostasis and uncontrolled bleeding may lead to transfusion and/or other bleeding-related complications4, lower clinical outcomes and higher hospital costs5.

During the last 20 years, FLOSEAL Hemostatic Matrix has been shown to result in better clinical and hospital resource utilization outcomes.

Take an Active Approach to Hemostasis

FLOSEAL consists of a unique combination of patented gelatin granules and human thrombin to provide fast (2 min median time to hemostasis), effective hemostasis. Learn more about how FLOSEAL works.

Additional Product Benefits

The Leader in Hemostasis

For certain surgical procedures, use of FLOSEAL Hemostatic Matrix is associated with shorter length of surgery6, fewer intensive care unit days7, significantly lower risks of minor complications, blood transfusions and surgical revisions8.

Consistent Performance

FLOSEAL has been proven to perform fast and consistently across a range of bleeds9*.

*Based on pre-clinical data.

Health Economic Benefits

The use of FLOSEAL can result in improved Resource Utilization Outcomes and substantial Cost Savings for hospitals – up to $1.5M per year for a hospital performing 245 mixed cardiac surgical procedures per year10 and $2,445 per spine procedure11.

FLOSEAL Hemostatic Matrix Indication

FLOSEAL Matrix is indicated in surgical procedures (other than ophthalmic) as an adjunct to hemostasis when control of bleeding by ligature or conventional procedures is ineffective or impractical.

Full important risk information

Do not inject or compress FLOSEAL Matrix into blood vessels. Do not apply FLOSEAL Matrix in the absence of active blood flow, e.g., while the vessel is clamped or bypassed, as extensive intravascular clotting and even death may result.

Do not use FLOSEAL Matrix in patients with known allergies to materials of bovine origin. Do not use FLOSEAL Matrix in the closure of skin incisions because it may interfere with the healing of the skin edges.

FLOSEAL Matrix contains Thrombin made from human plasma. It may carry a risk of transmitting infectious agents, e.g., viruses, and theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

FLOSEAL Matrix is not intended as a substitute for meticulous surgical technique and the proper application of ligatures or other conventional procedures for hemostasis.

Excess FLOSEAL Matrix (material not incorporated in the hemostatic clot) should always be removed by gentle irrigation from the site of application.

FLOSEAL Matrix swells by approximately 10% to 20% after product is applied. Maximum swell volume is achieved within about 10 minutes.

The safety and effectiveness of FLOSEAL Matrix has not been established in children under 2 years of age and pregnant women.

Do not use air to remove residual FLOSEAL Matrix from Applicator tip. The Applicator tips should not be cut. Do not use FLOSEAL Matrix on bone surfaces where adhesives, such as methylmethacrylate or other acrylic adhesives, will be required to attach a prosthetic device.

Rx Only. For safe and proper use of this device, refer to the full Instructions for Use.

FLOSEAL Full Instructions for Use: