General Surgery

Baxter understands that colorectal teams are faced with ever-increasing complexities—from preventing post-operative leakage to reducing the risk of surgical site infections. Baxter's hemostat, sealant and tissue repair products were created to work across procedures to address those issues that stand in the way of patient healing.

Key Procedures

Each colorectal procedure provides unique challenges that can cause complications for the healing process. Here are just a few examples.

Image of gloved hand holding Floseal in a syringe next to the Floseal logo


Controlling all types of bleeding is important during colectomy surgeries. When dealing with complete removal of the large intestine, FLOSEAL provides fast hemostasis (2 minutes median time to hemostasis)1 that improves the chances for better outcomes.

Learn more about FLOSEAL >

Image of Tisseel in applicator next to Tisseel logo


Accessing the surgical site in a laparoscopic colostomy can be challenging, in addition to working in a contaminated field which leaves patients more susceptible to infection.  The wide range of TISSEEL applicators provide solutions for these unique access challenges, allowing for precise application in the surgical field.2.

Learn more about TISSEEL >

Image of Veritas held with forceps next to the Veritas logo

Hernia Repair

In hernia repair procedures, it is especially critical to select the right materials to provide tissue reinforcement in challenging repairs. VERITAS Collagen Matrix, Baxter's biologic mesh, provides fast remodeling and high strength3,4.

Portfolio of Products

Indications and Important Risk Information

FLOSEAL Hemostatic Matrix Indication

FLOSEAL Matrix is indicated in surgical procedures (other than ophthalmic) as an adjunct to hemostasis when control of bleeding by ligature or conventional procedures is ineffective or impractical.

Full important risk information

Do not inject or compress FLOSEAL Matrix into blood vessels. Do not apply FLOSEAL Matrix in the absence of active blood flow, e.g., while the vessel is clamped or bypassed, as extensive intravascular clotting and even death may result.

Do not use FLOSEAL Matrix in patients with known allergies to materials of bovine origin. Do not use FLOSEAL Matrix in the closure of skin incisions because it may interfere with the healing of the skin edges.

FLOSEAL Matrix contains Thrombin made from human plasma. It may carry a risk of transmitting infectious agents, e.g., viruses, and theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

FLOSEAL Matrix is not intended as a substitute for meticulous surgical technique and the proper application of ligatures or other conventional procedures for hemostasis.

Excess FLOSEAL Matrix (material not incorporated in the hemostatic clot) should always be removed by gentle irrigation from the site of application.

FLOSEAL Matrix swells by approximately 10% to 20% after product is applied. Maximum swell volume is achieved within about 10 minutes.

The safety and effectiveness of FLOSEAL Matrix has not been established in children under 2 years of age and pregnant women.

Do not use air to remove residual FLOSEAL Matrix from Applicator tip. The Applicator tips should not be cut. Do not use FLOSEAL Matrix on bone surfaces where adhesives, such as methylmethacrylate or other acrylic adhesives, will be required to attach a prosthetic device.

Rx Only. For safe and proper use of this device, refer to the full Instructions for Use.

FLOSEAL Full Instructions for Use:

TISSEEL [Fibrin Sealant] Indications

Hemostasis: TISSEEL is a fibrin sealant indicated for use as an adjunct to hemostasis in adult and pediatric patients (> 1 month of age) undergoing surgery when control of bleeding by conventional surgical techniques (such as suture, ligature, and cautery) is ineffective or impractical. TISSEEL is effective in heparinized patients.

Sealing: TISSEEL is a fibrin sealant indicated as an adjunct to standard surgical techniques (such as suture and ligature) to prevent leakage from colonic anastomoses following the reversal of temporary colostomies.


Important Risk Information for TISSEEL [Fibrin Sealant]

For Topical Use Only. Do not inject TISSEEL directly into the circulatory system or into highly vascularized tissue. Intravascular application of TISSEEL can lead to intravascular coagulation, can result in life- threatening thromboembolic events, and can increase the likelihood and severity of acute hypersensitivity reactions in susceptible patients. To minimize the risk of intravascular application, exercise caution when using TISSEEL in surgery.

Do not use TISSEEL in individuals with a known hypersensitivity to aprotinin.

Do not use TISSEEL for treatment of severe or brisk arterial or venous bleeding. In these situations, TISSEEL will be washed away in the flow of blood before hemostasis can be attained.

Do not spray TISSSEEL where the minimum recommended distance from the applicator tip to the target site cannot be assured.

Hypersensitivity or allergic/anaphylactoid reactions can occur with the use of TISSEEL. Such reactions may especially be seen if TISSEEL is applied repeatedly over time or in the same setting, or if systemic aprotinin has been administered previously.

Aprotonin is known to be associated with anaphylactic reactions. Even in the case of strict local application of aprotinin, there is a risk of anaphylactic reactions to aprotinin, particularly in the case of previous exposure.

Discontinue administration of TISSEEL in the event of hypersensitivity reactions. Remove remaining product from the application site.

Air or gas embolism has occurred when fibrin sealant was administered using pressurized gas. This can occur if a spray device is used at higher than recommended pressures and in closer than recommended proximity to the tissue surface.

When using the EASYSPRAY device, or an equivalent spray device for open surgical procedures cleared by FDA, TISSEEL must not be sprayed in enclosed body areas and must be sprayed onto only visible application sites.

TISSEEL is denatured when exposing to solutions containing alcohol, iodine or heavy metals. If any of these substances have been used to clean the wound area, the area must be thoroughly rinsed before the application of TISSEEL.

Apply TISSEEL as a thin layer by dripping or spraying using cannula or spray set. Excess clot thickness can negatively interfere with wound healing.

The safety and effectiveness of TISSEEL used alone or in combination with biocompatible carriers in neurosurgical procedures or other surgeries involving confined spaces have not been evaluated; its use in this setting is not FDA approved.

TISSEEL is made from human plasma. It may carry a risk of transmitting infectious agents, e.g., viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

Please see accompanying full Prescribing Information


Veritas Collagen Matrix is intended for use as an implant for the surgical repair of soft tissue deficiencies: abdominal wall repair, breast reconstruction, and repair of ventral and hiatal hernias.
Veritas Collagen Matrix minimizes tissue attachment to the device in case of direct contact
with viscera.


Use of Veritas Collagen Matrix is contraindicated in patients with a known sensitivity
to bovine material.


As with any surgical procedure, adverse reactions are possible and include but are not limited to: infection, rejection, erosion, and allergic reaction.

VERITAS full Instructions for Use